GPT and uremia: Friedman’s test showed statistically significant changes over 0, 20 and 60 dpt in creatinine levels (P = 0.026, K = 0.502), AST (P = 0.012, K = 0.485), ALP (P < 0.001, K = 0.641), and marginally significant changes in uremia (P = 0.077, K = 0.420) and ALT (P = 0.082, K = 0.421).