Phospho-S6 labeling was also detected in the retinal ganglion cell layer, present in retinal ganglion cells and/or displaced amacrine cells (Fig. 7a, arrows).56 Regions of the Tg(flk1:RFP)is18/+ retina with dysplasia (Fig. 7c, d [bracket], e, f) or advanced tumor (Fig. 7g) showed phospho-S6 labeled cells distributed throughout the lesions. Here, KDR is linked to neoplasm.