To further demonstrate that local excessive activation of TGF‐β recruits nestin+ cells to prostate stroma during pathogenesis of prostatic hyperplasia, we generated Nestin‐Cre-ER, Tgfbr2flox/flox mice by crossing Nestin‐Cre-ER with Tgfbr2flox/flox. The gene discussed is TGFB1; the disease is benign prostatic hyperplasia.