GDAP1 and Alzheimer disease: Vocal cord paralysis has been reported as an early, severe and frequent symptom of GDAP1-associated neuropathy [CMT4A], often followed by diaphragmatic dysfunction [8], [9], [10], [11], [12], [13], and in both AD and AR forms of CMT2A (mutations in the MFN2 gene) [14], [15].