NME4 and cervical adenocarcinoma: Furthermore, in situ proximity ligation assay (PLA) in murine lung epithelial MLE-12 cells and human cervical adenocarcinoma HeLa cells showed that the hexameric intermembrane space protein, NDPK-D (or NM23-H4), binds cardiolipin and facilitates its redistribution to the OMM as a form of mitophagy-induction signal in association with OPA1 [117].