BIN1 and myotonic dystrophy type 1: Alternative splicing changes affecting BIN1 exon 11, DMD exon 78 and LDB3 exon 11 were also detected in differentiated DM1 muscle cell cultures but not in differentiated DM2 or Ctrl muscle cell cultures (Fig. 1C), in accordance with a previous report in affected muscles of a large cohort of DM1 patients (Nakamori et al., 2013).