MBNL1 and myotonic dystrophy type 1: Moreover, DM1 muscle cells show assessable DM1-associated molecular features including CUGexp-RNA nuclear aggregates that sequester MBNL1 and subsequent alternative splicing defects (Botta et al., 2013; Dansithong et al., 2005; Francois et al., 2011; Furling et al., 2001; Holt et al., 2007; Loro et al., 2010).