The interaction between Mycobacterium tuberculosis and HIV can cause elevation of viral load and decrease of CD4 + T lymphocytes count, leading to accelerated decline in the immune function and decreased survival [10] People living with HIV have been considered as being more likely to have unfavorable treatment outcomes of TB treatment, due to the complexity of the management of co-infection and to behavioral factors of this population [11]. This evidence concerns the gene CD4 and tuberculosis.