Cryptotanshinone has also demonstrated sensitizing effects to a broad range of anti-cancer agents including Fas/Apo-1, tumor necrosis factor-α, cisplatin, etoposide, and 5-FU by inducing ER stress, highlighting its therapeutic potential in the treatment of human hepatoma and breast cancer (Park et al. [19]). Here, FAS is linked to hepatocellular carcinoma.