This result was confirmed in the gel zymography that revealed gelatinolytic activities (Figure 3G); the breast tumor cells from fibroadenoma, phyllodes, luminal A, and HER2+ showed increased secretion of matrix metalloproteinase-2 and -9 (MMP-2 and MMP-9) following exposure to platelets, i.e., cultured with PRP supplementation. This evidence concerns the gene ERBB2 and Fibroadenoma.