The luminal B and HER2+ breast tumor cells from the patient with the highest Ki67 positive result, a result associated with the most malignant features in breast tumor luminal B and HER2+ subtypes, showed a clear EMT induction by the PRP supplementation, with N-cadherin upregulated and E-cadherin downregulated (Figure 4D and 4E). This evidence concerns the gene ERBB2 and breast neoplasm.