MMP2 and neoplasm: The matrix metalloproteinases (MMPs), such as MMP-2 (gelatinase A, 72 kDa gelatinase) and MMP-9 (gelatinase B, 92 kDa gelatinase), are a family of zinc-dependent endopeptidases that have been associated with the ability of tumor cells to degrade extracellular matrix (ECM) components during tumor cell invasion [9, 10].