In the human endometrium and placenta, IL11 activates the janus kinase and signal transducers and activators of transcription (JAK/STAT3) pathway [8, 9] STAT3 is constitutively active in many human cancers, including endometrial cancer [10] and has the capacity to promote epithelial tumour growth [11]. The gene discussed is STAT3; the disease is endometrial cancer.