ZDHHC5 was previously seen involved in neoplasia with different partners: a ZDHHC5-SMTNL1 fusion was found in SCC of the ovary, a CTNND1-ZDHHC5 in adenocarcinoma of the lung, ZDHHC5-LCT in adenocarcinoma of the breast, and MEF2D-ZDHHC5 in grade III-IV astrocytoma of the brain [13]. Here, SMTNL1 is linked to brain astrocytoma.