We found that serum ALT (HR, 1.717; 95% CI, 1.172 to 2.515, P = 0.006), tumor size (HR, 1.789; 95% CI, 1.241 to 2.577, P = 0.002), tumor differentiation (HR, 1.751; 95% CI, 1.244 to 2.464, P = 0.001), tumor number (HR, 1.463; 95% CI, 1.003 to 2.133, P = 0.048) and GFAT1 expression (HR, 2.139; 95% CI, 1.441 to 3.174, P < 0.001) showed a significant risk in multivariate analyses and were determined as independent prognostic factors of OS (Figure 3A). This evidence concerns the gene GFPT1 and neoplasm.