Moreover, in two dimensional culture, XIAP 3′UTR transfected cells assumed a scattered and spindle-like morphology whereas control cells were tightly interconnected and exhibited an epithelial-like morphology, demonstrating XIAP 3′UTR may regulate breast cancer cytoskeletal dynamics which is often linked to cell motility and metastatic potential (Figure 3G). The gene discussed is XIAP; the disease is breast carcinoma.