In the Khambata–Ford (KF) cohort, the KRAS mutation status was highly sensitive but not very specific, because of a number of WT-KRAS tumours that did not respond to cetuximab (of note, the BRAF status was not tested in this retrospective study), whereas the OT mini-classifier exhibited higher sensitivity (0.83), and specificity (0.86) (without stable disease). This evidence concerns the gene BRAF and neoplasm.