Telomerase reconstitution by reactivating TERT expression is known to occur in cancers by various mechanisms that involve oncogenic transcription factors, gene amplification, promoter mutations, crosstalk with oncogenic pathways or epigenetic regulation (Akincilar et al., 2016b; Li and Tergaonkar, 2016; Li et al., 2016; Tergaonkar, 2016). Here, TERT is linked to cancer.