ROC curve showed that the cutoff values of autoantibody against PRDX2 and PRDX3 were 0.173 and 0.608, respectively, with sensitivities/specificities of 26.4/96.0, 24.5/95.0%, and AUC values of 0.614 (95% CI 0.542–0.686) and 0.600 (95% CI 0.528–0.673) for discriminating NPC from normal controls (Fig. 3, Table 3). Here, PRDX2 is linked to nasopharyngeal carcinoma.