AGER and gastric cancer: The aims of the present case–control study were to determine (1) the relationship between four well-characterized polymorphisms in the RAGE gene (rs1800624 [−374T>A], rs1800625 [−429T>C], rs184003 [1704G>T], and rs2070600 [Gly82Ser]) and the risk of gastric cancer in a southwest Han Chinese population; (2) the association between sRAGE levels and gastric cancer; and (3) the association between RAGE polymorphisms and sRAGE levels.