FFAR4 and obesity due to melanocortin 4 receptor deficiency: The relatively high expression of GPR120 in adipose tissue, macrophages, and intestine has resulted, to date, in a focus on its contribution to insulin signaling, obesity, and anti-inflammatory responses and, on the basis of these, the potential for GPR120 agonists to regulate glucose homeostasis and act as potential medicines to treat type II diabetes (7).