Finally, Abbott et al. (1998) [25] administered testosterone propionate for 15–88 days, starting at various gestational ages, and found consistent reproductive features similar to clinical PCOS in female rhesus macaque offspring, such as increased serum testosterone and LH levels, lower follicle stimulating hormone (FSH) levels, and ovaries containing multiples cystic follicles. The gene discussed is PLOD1; the disease is polycystic ovary syndrome.