Variants at the PTPN22, STAT4, TNF-α, TNFAIP3, MIF, WISP3, SLC11A1 and IL2-Ra loci have been reported as risk factors for JIA by several investigators [5], although it was also reported that several of these are not necessarily shared between different ethnic groups [10,30]. The gene discussed is STAT4; the disease is juvenile idiopathic arthritis.