SMARCA4 and retinoblastoma: BRG1 is upregulated and correlated with tumor proliferation in gastric cancer and contributes to acute myeloid leukemia maintenance.7, 8 Napolitano et al.9 and Kang et al.10 reported that Brg1 induces senescence and inhibits cell proliferation in rat mesenchymal stem cells and retinoblastoma, respectively.