TH and Parkinson disease: This model causes striatal dopamine depletion nearly 50% in C57BL/6 mice, and the DA lesion stabilizes by 21 days after MPTP administration.39, 40 Besides, in this study, we focus on the expression changes of GLTs in PD and according to our previous work, we find the decreased GLTs, TH expression and movement disorder in different time points in the subacute MPTP model (unpublished data).