KDR and neoplasm: The results showed that high-dose cRGD-siEGFR (5 nmol/20 g), cRGD-Vegfr2 siRNA (1.5 nmol/20 g) and low-dose cRGD-siEGFR (1.5 nmol/20 g) significantly inhibited tumor growth, compared with the saline group; the weight or cumulative growth of the volume of tumors was reduced by approximately 50%, 32% and 27%, respectively.