KDR and neoplasm: Compared with saline-treated groups, cRGD-siEGFR (5 nmol/20 g) and cRGD-Vegfr2 siRNA (1.5 nmol/20 g) inhibited tumor growth significantly, beginning at 4 days after the second injection (p < 0.05), and low-dose cRGD-siEGFR (1.5 nM/20 g) inhibited tumor growth significantly beginning at 6 days after the third injection (p < 0.05).