PMEL and melanoma: To examine this question, we generated a list of 83 differentiation-associated genes (that is, PMEL, TYR, TYRP1, DCT, SLC45A2, MLPHA, MLANA) derived from the GSEA analysis above as well as the ZFIN database (http://zfin.org/), and then assessed how their expression correlated with survival in the TCGA melanoma cohort.