SSTR5 and pituitary gland adenoma: Further support that the low sst5 expression level in the stimulated-population of GHomas and ACTHomas may serve as a potential signature to distinguish between the differential response of pituitary adenomas is provided by a previous study in patients with TSHomas, which showed that tumors displaying a stimulatory response to octreotide expressed relatively low levels of sst5 in comparison with sst2, while tumors with higher sst2 than sst5 expression obtained a beneficial response to octreotide25.