Interestingly, when results from both GHomas and ACTHomas are viewed together, we observed two common, distinctive molecular signatures, namely, a lower sst5 expression in stimulated vs. inhibited pituitary adenomas, and a higher D2 expression level as compared with sst5 expression in stimulated pituitary adenomas. The gene discussed is SSTR5; the disease is ACTH-producing pituitary gland adenoma.