IL10 and colitis: In 2015, a study comparing Lc. lactis NZ9000 (NZ9000) that secreted serine protease inhibitors (elafin or secretory leukocyte protease inhibitor) to NZ9000 that secreted the anti-inflammatory cytokines IL-10 or transforming growth factor-β showed that the former significantly attenuated the symptoms of dextran sodium sulfate (DSS)-induced colitis (33).