In the first of these reports, preventive daily oral administration of α-MSH-secreting B. longum HB15 (HB15) markedly reduced histopathological damage, increased myeloperoxidase activity, corrected an inflammatory/anti-inflammatory cytokine imbalance, and induced production of the pro-inflammatory factor nitrogen monoxide, overcoming effects caused by DSS colitis in rats. Here, STAMBP is linked to colitis.