ESRRB and neoplasm: The concurrent ERRB2 amplified and KRASG12D mutated tumor was found in a 58-year-old male with moderately differentiated rectal adenocarcinoma with synchronous solitary liver metastasis treated with neoadjuvant 5-FU, oxaliplatin (FOLFOX) followed by hepatic resection and resection of primary – he is currently under surveillance and without evidence of disease.