IFNG and neoplasm: Consistent with its ability to increase or decrease tumor-infiltrating immune cells (Figure 7C, 7D), or increase IFN-γ secretion (Figure 7E) or increase significantly active dendritic cells and decrease regulatory T cells (Figure 7G, 7H), MART1 and virus in AdMGshT treatment induced the greatest anti-tumor effect in immunecompetent mouse-model system suitable for our oncolytic adenovirus.