To identify the types of infiltrating immune cells in tumor tissues, tumor sections were examined by immunohistochemistry using anti-CD4, anti-CD8, anti-NK1.1, or CD11b+c antibody for the detection of CD4+ T cell, CD8+ T cell, NK cell or NK T cell, and macrophage or dendritic cell, respectively (Figure 4C). This evidence concerns the gene CD8A and neoplasm.