Some studies have shown acceptable diagnostic value on the part of circulating visfatin levels for the detection of early CRC (sensitivity= 68.2% and specificity=70.8%, AUC=0.812)[32] and postmenopausal breast cancer (sensitivity= 97.6% and specificity=92.6%, AUC=0.724)[33]. The gene discussed is NAMPT; the disease is breast carcinoma.