Visfatin is upregulated during adipocyte differentiation and has insulin-like activity under physiological conditions; hence, elevated visfatin levels have been found to be positive correlated with metabolic syndromes, such as polycystic ovary syndrome [7], type 2 diabetes mellitus (T2DM) [8], and cardiovascular diseases [9]. The gene discussed is INS; the disease is type 2 diabetes mellitus.