Additionally, only participants with BMI<25 kg/m2 were included in this study, therefore, the role of visfatin in HCC in obese patients remains unclear; in addition, the relation between visfatin levels and the other index of of visceral fat mass, such as waist circumference, waist-hip ratio, lipid accumulation product, are not evaluated and adjusted in this study, which might produce potential bias for our results, as visfatin is upregulated during adipocyte differentiation. This evidence concerns the gene NAMPT and hepatocellular carcinoma.