Immunohistochemical staining grade for both FL-MMP-2 and NTT-MMP-2 was higher in diabetic kidney disease as compared to controls (FL-MMP-2: 1.8±0.9 vs. 2.5±0.5, p = 0.03; NTT-MMP-2: 0.9±0.7 vs. 2.4±0.6, p<0.001) (Fig 6, Panel II). The gene discussed is MMP2; the disease is diabetic kidney disease.