For instance, Su [12] treated the mice suffering cerebral ischemia with rapamycin, and found that rapamycin could up-regulate the phosphorylation level of mTOR protein and reduce the cerebral infarct area, which indicated that the protective effect of a trace amount of rapamycin on acute cerebral ischemic injury was correlated with the activation of mTOR signal pathway. The gene discussed is MTOR; the disease is Cerebral ischemia.