Of the remaining three NF2 wild-type meningiomas which also lack other known meningioma-driver mutations: i) Case 2 contained deletions of BARD1, SMARCAL1 and two histone members, as well as mutations in NF1, DDR1, BCL11A and ATF6B; ii) Case 3 harbored deletions on Chromosome 2q containing CASP8, CASP10, BARD1 and SMARCAL1, and amplifications on Chromosome 6p containing DAXX and three histone members; iii) Case 6 harbored amplifications on Chromosome 6p containing NOTCH4 and four histone members. Here, CASP8 is linked to meningioma.