Additionally, our results also demonstrated the mRNA of KLK4 expression had no significant correction with the expression of miR-422a in NSCLC samples (r2 =0.0171, P =0.1559), and miR-422a did not affect the mRNA of KLK4 in NSCLC cell lines. The gene discussed is KLK4; the disease is non-small cell lung carcinoma.