ZP4 and infection: Surprisingly, the STING/TBK1 axis was not differentially expressed in our dataset but the genes for other DNA sensors such as Dai (Zbp) and Ifi204, and for RNA sensors such as RIG-I (Ddx58), LGP2 (Dhx58), and MDA5 (Ifih1) were induced, as were the downstream transcription factors NF-κB, IRF7, IRF9, STAT1 and STAT2, the effectors IFNβ and IL-1β, and many of the ISGs, particularly in BMDMs (at both time points, and either upon infection with live bacteria or stimulation with dead bacteria), but only marginally in J774 infected with live bacteria at 24 hpi.