In the eye at E16.5 (Fig. 5a), the strongest Adamts17 expression was detected in lens fiber cells at the lens equator, the site of the insertion of the ciliary zonule which is defective in ectopia lentis, in the non-pigmented epithelium of the ciliary body, which is the other attachment site of the zonule, and in the trabecular meshwork, which if blocked, can lead to glaucoma. The gene discussed is ADAMTS17; the disease is glaucoma.