ANO5 and gnathodiaphyseal dysplasia: Previously five mutations in the ANO5 gene had been identified for GDD which affect cysteine 356 (p.Cys356Gly and p.Cys356Arg), threonine 513 (p.Thr513Ile) and serine 500 (p.Ser500Phe)6, 10, 11.