In case of Caki‐1 renal cell carcinoma cells, cell proliferation/survival decreased after FANCD2 knockdown with FANCD2 siRNAs (siFD2#2 or siFD2#4) compared with control siRNA‐transfected cells (siControl) at the AICAR concentration of 0.12 mm in MTT assay (Fig. 4D). The gene discussed is FANCD2; the disease is hereditary clear cell renal cell carcinoma.