TNF and acute kidney injury: Huang‐Lian‐Jie‐Du‐Decotion and its four component herbs inhibited the phosphorylation of p38, Erk, and NF‐kB‐p65, and suppressed the expressions of iNOS, COX‐2, IL‐6, and TNF‐α induced by LPS, which suggested that HLJDD and its component herbs could ameliorate LPS‐induced inflammatory responses by inhibiting MAPK signaling pathway, thus exhibiting anti‐inflammatory protection on LPS‐induced AKI.