TNF and osteoporosis: When studying NR_024031, also named DANCR, researchers found that DANCR promoted the expression of IL-6 and TNF-α, and DANCR-induced IL-6 and TNF-α had bone-resorbing activity indicating that DANCR is involved in the pathology of osteoporosis and may be a biomarker for postmenopausal osteoporosis [63].