Supplementary Figure 3 shows these entrainment differences for females (Supplementary Figure 3a), males (Supplementary Figure 3b) and both genders (Supplementary Figure 3c). Both PTSD and healthy controls peak after sunrise. However, ~70% of female PTSD patients and 80% of male PTSD patients show extended elevation of the MCP4/MCP-1 ratio beyond time Z=6 h. However, based on P-values, Supplementary Figure 3d shows that these differences only trend towards significance. This evidence concerns the gene CCL2 and post-traumatic stress disorder.