IL6 and monocytic leukemia: sST2 down-regulates LPS-induced IL-6 production from a human monocytic leukemia cell line via the suppression of NF-κB binding to the IL-6 promoter [116], and sST2 can be internalized into dendritic cells and suppresses LPS signaling and cytokine production in human monocyte-derived dendritic cells without attenuating the LPS-induced dendritic cell maturation [117].