Therefore in this article we perform a meta-analysis of RCTs comparing cetuximab plus chemotherapy with chemotherapy alone with the aim of identifying whether cetuximab plus chemotherapy improves the outcomes of R0 resection rate, overall response rate, progression-free survival, and overall survival of KRAS wild type patients only with colorectal cancer liver-limited metastases or not at a higher level of evidence-based medical evidence. Here, KRAS is linked to colorectal cancer.