miRNAs-dependent regulation of NCOR proteins is supported by two studies showing that (i) miR-16 in LPS-activated human monocytes (U937) and biliary epithelial cells (H69) targets SMRT (NCOR2), which leads to NF-κB-mediated transactivation of the IL-8 gene [107], and (ii) miR-100 targets SMRT (NCOR2) in glioblastoma cells thereby inhibiting their proliferation [112]. This evidence concerns the gene NCOR2 and glioblastoma.