PPARA and prostate adenocarcinoma: In another study, the growth inhibitory properties of 1.25-dihydroxyvitamin D3 in human prostate adenocarcinoma cells (LNCaP) were associated with an increased expression of the miR-17/92 cluster, which correlated with PPARα downregulation, but whether miR-17/92 directly target PPARα was not investigated [77].