Given the critical role of CCL2 in the proinflammatory process and its implication in neuroinflammation underlying the pathogenesis of certain CNS diseases, e.g., Alzheimer’s disease (41–45), it is postulated that the elevated CCL2 levels observed in the present study may indicate neuroinflammation in ASD. The gene discussed is CCL2; the disease is early-onset autosomal dominant Alzheimer disease.