NPC1 and nasopharyngeal carcinoma: To generate a mouse model mimicking the phenotype of NPC patients with the mutations c.1554-1009 G > A and c.1920delG, Ozgene generated two strains of mice, each bearing one of these two NPC1 mutations in heterozygosity, and named them “Imagine” (I, c.1554-1009 G > A) and “Pioneer” (P, c.1920delG).