PGF and preeclampsia: Although the POP study included mostly healthy women, this is consistent with the findings in women clinically suspected to have preeclampsia, where an elevated sFlt-1:PlGF ratio between 24 and 37 wkGA was also associated with an increased risk of developing the disorder within 4 weeks after the measurement.16 Hence, although the test provides clinically useful prediction of risk for a small proportion of women, the majority of women experiencing the disease would not be identified using the test at 28 wkGA.