ELP2 and amyotrophic lateral sclerosis: Variants in the ELP2 gene are associated with neurodevelopmental (including intellectual) disability (Cohen et al., 2015; Franic et al., 2015) while ELP3 variants are associated with ALS (Simpson et al., 2009; Kwee et al., 2012), and loss of ELP4 can cause Rolandic epilepsy syndrome and intellectual disability (Strug et al., 2009; Nguyen et al., 2010; Gkampeta et al., 2014; Reinthaler et al., 2014; van Blitterswijk et al., 2014; Addis et al., 2015).