FCGR2B and atherosclerosis: However, the role of this receptor is not yet clear, since recently it was reported that FcγRIIB deficiency reduces atherosclerosis in hyperlipidemic Apoe−/− mice, as well as induction of T regulatory cells and increased secretion of atheroprotective cytokines such as IL10 and TGFβ, which are partially responsible for the attenuation of the disease [72].