In T2D rats, serum ALP, ALT, AST, and urea contents were significantly elevated after NA-STZ treatment, but significantly decreased in EAF treated rats without alteration of creatinine levels, indicating that EAF did not cause any damage to the liver and kidney when treated up to 50 mg/kg b.w. Hyperlipidemia is one of the major factors linked with hyperglycemia due to insulin deficiency during diabetes and correlated with carbohydrate metabolism. This evidence concerns the gene GPT and type 2 diabetes mellitus.